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姓名:谭小娟

职称:特任副教授

电话:0553-3869297

邮箱:xjtan@ahnu.edu.cn

主要学习工作经历

   20161月,南京理工大学,博士学位

   2019年至今,bv伟德国际体育,bevictor伟德

   20162月至20191月,国外博士后

主要社会兼职

   安徽省细胞生物学学会 会员

   bv伟德国际体育科技协会 会员

主要研究内容

病原菌耐药机制及非经典抗菌靶标研究

慢性伤口细菌生物被膜形成的分子机制和诊断标志物研究

水稻生防菌筛选和分子机制研究

主要研究课题

1.国家自然科学基金青年项目,碱性磷酸酶LapA在慢性伤口铜绿假单胞菌生物被膜形成中的调控机制,322001522023.01-2025.12,在研,主持。

2. 安徽省自然科学基金青年项目,慢性伤口铜绿假单胞菌生物被膜形成相关sRNA筛选、鉴定及作用机理研究,2108085QC922021.01-2022.12在研,主持。

3.分子酶学与重大疾病机理研究安徽省重点实验室开放课题,慢性伤口铜绿假单胞菌生物被膜的诊断标志物研究,fzmx2020052021.01-2023.12,在研,主持。

4. 安徽省科技重大专项项目,皖江流域水稻病虫害绿色防控体系的建立、集成与示范,202003a060200092020/10-2023/09,在研,参与。

5. 安徽省高校自然科学研究重点项目,慢性皮肤伤口表皮葡萄球菌生物被膜的诊断标志物研究,KJ2019A05052019.01-2021.12,结题,主持。

6. bv伟德国际体育博士科研启动金项目,慢性伤口金黄色葡萄球菌生物被膜的诊断标志物研究,2020/01-2022/12在研,主持。

主要研究成果

一、代表性论文及论著:

1. Xiao-Juan Tan; Zhi-Wei Zhang; Jing-Jing Xiao; Wei Wang; Feng He; Xuan Gao; Bin Jiang; Liang Shen; Xu Wang; Yang Sun; Guo-Ping Zhu ; Genomic and phenotypic biology of a novel Dickeya zeae WH1 isolated from rice in China: Insights into pathogenicity and virulence factors, Frontiers in Microbiology, 2022, 13: 997486.

2. Xiaojuan Tan*, Xi Cheng, Mei Hu, Yifan Zhang, Aiqun Jia, Jinwei Zhou*, Guoping Zhu*. Transcriptional analysis and target genes discovery of Pseudomonas aeruginosa biofilm developed ex vivo chronic wound model. AMB Express, 11, 157 (2021).

3. Jinwei Zhou, Aiqun Jia*, Huan Jiang, Peili Li, Hong Chen, Xiaojuan Tan*, Enqi Liu*. 1-(4-Amino-2-hydroxyphenyl) ethanone from Phomopsis liquidambari showed quorum sensing inhibitory activity against Pseudomonas aeruginosa. Applied Microbiology and Biotechnology, 105:341–352 (2021).

4. Jinwei Zhou, Aiqun Jia*Xiaojuan Tan*, Hong Chen, Bing Sun, Tianzi Huang, Yu He, Peili Li, Enqi Liu*, 1-(4-Amino-2-hydroxyphenyl) ethanone suppresses Agrobacterium tumefaciens virulence and metabolism, Frontiers in Microbiology, 11,584767 (2020).

5. Yi Wang, Xiaojuan Tan, Chuanwu Xi, K. Scott Phillips*. Removal of Staphylococcus aureus from skin using a combination antibiofilm approach. NPJ Biofilms and Microbiomes, 4, 16 (2018).

6. Jinwei Zhou, Tongtong Chen, Xiaojuan Tan, Jiyang Sheng, AiqunJia*. Can the quorum sensing inhibitor resveratrol function as an aminoglycoside antibiotic accelerant against Pseudomonas aeruginosa? International Journal of Antimicrobial Agents, 52(1):35-41 (2018).

7. Xiaojuan Tan#, Nan Qin#, Chunyan Wu, Jiyang Sheng, Rui Yang, Beiwen Zheng, Lin Liu, Xinhua Peng*, Aiqun Jia*. Transcriptome analysis of the biofilm formed by methicillin-susceptible Staphylococcus aureusScientific Reports, 5, 11997 (2015).

8. Nan Qin#, Xiaojuan Tan#, Yinming Jiao#, Lin Liu, Wangsheng Zhao, Shuang Yang, Aiqun Jia*. RNA-Seq-based transcriptome analysis of methicillin-resistant Staphylococcus aureus biofilm inhibition by ursolic acid and resveratrol. Scientific Reports, 4, 5467 (2014).

9. Xiaojuan Tan#, Lin Liu#, Shili Liu, Dongting Yang, Yikun Liu, Shuang Yang, AiqunJia*, Nan Qin*. Genome of Staphylococcus xylosus and Comparison with S. aureus and S. epidermidisJournal of Genetics and Genomics, 41:413-416 (2014).

10. Xiaojuan Tan, Dongting Yang, Guoxu Yang, Jinhui Chen, Wei Dong, Jisen Shi, AiqunJia*. The investigation of inhibiting quorum sensing and methicillin-resistant Staphylococcus aureus biofilm formation from Liriodendron hybrid. Pakistan Journal of Pharmaceutical Sciences, 28:903-908 (2015).

11. 刘琳#, 谭小娟#,贾爱群*.细菌群体感应与细菌生物被膜形成之间的关系.微生物学报,52, 271-278 (2012).